摘要
①目的 探讨白细胞介素 6 (IL 6 )水平与不稳定型心绞痛 (UAP)病人预后的关系。②方法 采用ELISA法测定 92例UAP病人、46例稳定型心绞痛 (SAP)病人和 2 2例健康人血清IL 6水平 ;对心绞痛病人进行 180d的随访 ,记录心脏事件的发生情况。③结果 UAP组病人血清IL 6水平明显高于SAP组和健康组 (F =7.78,q =3.0 6 ,7.0 3 ,P <0 .0 1) ,UAP组随访 180d内心脏事件的发生率明显高于SAP组 (χ2 =4.0 4,P <0 .0 5 )。④结论 UAP病人血清中IL 6的水平普遍升高 ,其升高与UAP病人的不良预后有关 ;IL
Objective\ To study the correlation between the level of IL 6 and prognosis of the patients with unstable angina. \ Methods\ The level of IL 6 in 92 patients with unstable angina , 46 patients with stable angina and 22 healthy subjects, for control, were measured. The patients with angina were followed for 180 days. The events on heart attacks were recorded.\ Results\ We found that the level of IL 6 was significantly elevated in patients with unstable angina compared with the patients with stable angina and healthy subjects( F=7.78, q=3.06,7.03,P <0.01). The rate of heart attacks in patients with unstable angina was significantly higher than that of patients with stable angina( χ 2=4.04, P < 0.05 ).\ Conclusion\ Our study demonstrates that elevated level of IL 6 in unstable angina was common and the elevation was correlated with poor prognosis. The detection of IL 6 may have an important significance in explaining the mechanism of the disease and predicting the prognosis.
出处
《齐鲁医学杂志》
2001年第3期198-199,共2页
Medical Journal of Qilu
