摘要
目的探讨血清降钙素原(PCT)及白介素6(IL-6)检测在慢性阻塞性肺疾病(COPD)诊治中的意义。方法采用电化学发光分析法检测160例COPD患者(观察组)及110例健康对照者(对照组)的PCT及IL-6水平,并比较2组敏感性和特异性。结果观察组PCT、IL-6的水平均显著高于对照组(P<0.05);IL-6敏感性高于PCI(P<0.05),而PCT特异性高于IL-6(P<0.05)。结论 PCT和IL-6检测在COPD诊治中具有重要的临床价值,但二者在敏感性和特异性上存在差异。
Objective To explore clinical significance of serum procalcitonin （PCT）and in-terleukin-6 （IL-6）detection in the diagnosis and treatment of patients with chronic obstructive pul-monary disease （COPD）.Methods Electrochemical luminescence analysis was used to detect the levels of PCT and IL-6 in 160 COPD patients （observation group）and 110 normal people （control group）,and sensitivity and specificity of PCT and IL-6 were compared.Results Levels of PCT and IL-6 in the observation group were significantly higher than those in the control group （P 〈0.05）.Sensitivity of IL-6 was significantly higher than that of PCT （P 〈0.05）,while specificity of PCT was significantly higher than that of IL-6 （P 〈0.05）.Conclusion PCT and IL-6 detec-tion play an important role in the diagnosis and treatment of COPD,but there are differences of sen-sitivity and specificity between PCT and IL-6 detections.
出处
《实用临床医药杂志》
CAS
2014年第9期144-145,共2页
Journal of Clinical Medicine in Practice
关键词
慢性阻塞性肺病
降钙素原
白介素-6
hronic obstructive pulmonary disease
procalcitonin
interleukin-6
