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自身免疫性甲状腺疾病与细胞凋亡 被引量:2

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摘要 自身免疫性甲状腺疾病细胞凋亡存在异常,桥本甲状腺炎时,甲状腺细胞Fas表达增强,诱导细胞凋亡,造成甲状腺组织的损伤。Graves病时因Fas表达减弱,bcl-2表达增强而阻止了凋亡发生,从而造成甲状腺滤泡上皮细胞增生肥大。一些物质可以上调或者下调甲状腺细胞Fas表达,因此,可能为自身免疫性甲状腺疾病开拓一条新的治疗途径。
出处 《国外医学(内科学分册)》 2001年第9期399-401,共3页 Foreign Medical Sciences(Section of Internal Medicine)
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同被引文献48

  • 1曹峰林,禹宏,吴丽杰,申秀玲.Graves病与人类MHC-DR基因的关联研究[J].中国地方病防治,2006,21(1):14-15. 被引量:1
  • 2陈威,满娜,李玉姝,单忠艳,滕卫平.血清甲状腺自身抗体、碘摄入量与Graves病发病及临床转归的关系[J].中华内科杂志,2006,45(2):95-99. 被引量:24
  • 3董吉祥,谢莹,汪寅,石永兵,沈华英,刘志达,韩惠琴,谢炜,张学光.Graves病患者外周血IL-6、TNF-α水平表达的变化及意义[J].中国免疫学杂志,2006,22(4):378-380. 被引量:14
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