摘要
目的 监测阻塞性睡眠呼吸暂停综合征 (OSAS)患者的夜间血氧饱和度 (SaO2 )和呼气末二氧化碳分压 (PetCO2 ) ,以比较其临床价值。方法 对 2 5例OSAS患者同步进行多导睡眠图、SaO2 和PetCO2 监测 ,并对有关SaO2 和PetCO2 的指标进行对比。结果 伴有SaO2 下降的呼吸紊乱总频率 ( 75.2± 2 7.8) %较伴有PetCO2 上升的呼吸紊乱总频率 ( 2 7.2± 1 7.4) %明显高 (P <0 .0 0 1 )。平均SaO2 、最低SaO2 和伴氧饱和度下降≥ 4%的平均SaO2 与AI、AHI呈负相关 ;T 90 %与AI、AHI呈正相关。夜间平均PetCO2 和最高PetCO2 与AI、HI、AHI比较均无显著相关性。结论 夜间氧饱和度监测对OSAS筛选具有明确临床意义 ;PetCO2 监测对判断OSAS病情有价值 ;但PetCO2 不及SaO2 敏感 ,需大样本多中心进一步研究。
Objective To investigate the clinical significance of SaO 2 and PetCO 2 to detect obstructive sleep apnea syndrome (OSAS). Methods Polysomnography (PSG), pulse oximeter and capnography monitoring were performed simultaneously in 25 patients. The parameters related with SaO 2 and PetCO 2 were compared. Results The frequence of respiratory disturbance with desaturation was significantly higher than that with PetCO 2 ascending [(75.2±27.8)% vs (27.2±17.4)%, P<0.001].The mean and lowest nocturnal SaO 2, mean SaO 2 with desaturation value higher than 4% were negatively correlated with apnea index (AI) and apnea hypopnea index (AHI). T 90% was positively correlated with AI and AHI. The mean and the highest nocturnal PetCO 2 weren't significantly correlated with AI and AHI. Conclusion Nocturnal SaO 2 monitoring is a simple and valuable method for the diagnosis of OSAS. PetCO 2 monitoring can provide useful information about patients' condition. Its validity and its sensitivity for the detection of OSAS will be subject of a subsequent study.
出处
《临床内科杂志》
CAS
北大核心
2001年第5期347-349,共3页
Journal of Clinical Internal Medicine
