摘要
目的 :探讨蛋白 S在脑梗死中的改变。方法 :脑梗死患者 42例 ,健康体检者 40例作为对照。使用自动凝血仪检测蛋白 S活性 ,EL ISA法检测总和游离蛋白 S抗原含量。结果 :42例脑梗死患者中检出 7例蛋白 S活性缺乏 ,其中仅有 2例伴有游离蛋白 S抗原严重下降。结论 :脑梗死中存在蛋白 S活性缺乏 ,但并不与游离蛋白
Objective: To investigate changes of plasma protein S in ischaemic stroke.Methods: Forty two patients with ischemic stroke and 40 healthy volunteers were enrolled in this trial.Plasma protein S activity was detected by clotting assay on the ACL 300 automantic coagulation laboratory;total and free PS were determined by enzyme linked immunosorbant assay(ELISA).Results: Among 42 patients, 7 with protein S activity dificiency were found while only 2 of them showed marked decrease in antigens of free protein S. Conclusion:Protein S deficiency may develop in ischemic stroke patients,however 70% of them do not have a current decrease of antigen of free PS.
出处
《浙江大学学报（医学版）》
CAS
CSCD
2001年第4期153-154,182,共3页
Journal of Zhejiang University(Medical Sciences)
关键词
病因学
蛋白质S缺乏
并发症
Cerebral infarction/etiol
Protein S,deficiency/compl
Ischemic stroke
