摘要
目的 明确医院感染性微生物主要分布及体外耐药情况。方法 参照全国医院感染中心制定的医院感染诊断标准 ,对我院 1995年 1月至 1998年 12月共出院 3142 4人次进行调查 ,有 1783人次发生医院感染 ,并对其进行分析 ,对造成医院感染的主要病原菌进行体外药物敏感试验测定。结果 医院感染发生率为 5 6 7% ,发生感染部位以呼吸道最高为 46 43 % (上呼吸道为 2 5 78% ,下呼吸道为 2 0 6 5 % ) ,其次为手术伤口占 18 5 8%、泌尿道为 16 3 %。引起医院感染病原微生物以G+菌为主占 5 8 2 2 % ,G-菌为 2 7 85 % ,真菌为 13 93 %。药敏测定发现医院感染性病原菌存在着日益严重和复杂的耐药性。结论 呼吸道、手术伤口和泌尿道是医院感染控制的重点 ,耐药及多重耐药菌株日益增多。提示应加强医院感染管理 ,重视抗生素合理应用和微生物监测 。
Objective: To investigate the main distribution of infectious microorganisms and spectrum of drug tolerance in vitro. Methods: Thirty one thousand four handred and twenty four patients discharged from our hospital during 1995, 1～1998, 12 were studied, among whom 1783 patients got infection, and the main pathogenic bacteria leading to hospital infection were detected with drug allergic test. Results: The rate of hostpital infection was 5 67%. The rate of infection in respiratory tract was the highest (46 43%), in upper respiratory tract 25 78%, in the lower respiratory tract 20 65%. The rates of infection in urologic tract and surgical trauma was 18 58% and 16 3% respectively. The microorganisms led to hospital infection were G -bacteria(58 22%), G + bacteria(27 85%) and fungus (13 93%). Drug allergic test found the pathogenic bacteria leading to hospital infection had severe and complicate drug tolerance. Conclusion: More attention should be paid to respiratory tract, urologic tract and surgical trauma in comtrolling hospital infection. Drug tolerance bacteria are increasing, which suggusts that it is important to reinforce the management of hospital infection, to pay more attention to using antibiotics and detecting microorganisms, and to decrease hospital infection to the lowest level.
出处
《泰山医学院学报》
CAS
2001年第2期123-126,共4页
Journal of Taishan Medical College
