摘要
应用毛细管电泳法测定了复方磷酸可待因溶液中磷酸可待因、盐酸麻黄碱、扑尔敏的含量。毛细管电泳的条件为 :37cm× 5 0 μm i.d(有效长度 30 cm)未涂层石英毛细管柱 ;分离电压 :1 5 k V;缓冲溶液 1 5 0 mmol/L NH4 Ac- H3PO4 ( p H2 .0 )。研究了方法的线性范围、精密度、回收率等 ,测定了三批样品。实验证明方法简便、快速。
A new capillary electrophoresis method has been developed for the determination of codeine phosphate, ephedrine hydrochloride and chlorpheniramine maleate in compound codeine phosphate solution. The method employed a 150 mmol/L ammonium acetate phosphoric acid (pH 2.0) buffer solution, UV detection at 214 nm, electrophoresis voltage 15 kV and a capillary of 50 μm(i. d.)×37 cm. The established procedure has been applied to the determination of three batch samples. The result indicated that the proposed method was simple, rapid and reliable.
出处
《分析科学学报》
CAS
CSCD
北大核心
2001年第3期182-185,共4页
Journal of Analytical Science
基金
国家自然科学基金 (No.2 963 5 0 2 2 0 )
