摘要
为监测血管紧张素 ( angiotensin ,AT- )水平在肝脏疾病介入治疗前、后的变化 ,及评价 AT- 作为介入治疗疗效判定指标的可靠性 ,本文对 56例肝硬变门脉高压伴顽固性腹水 ,经颈静脉肝内门腔静脉分流术( TIPS)患者 ,采用 RIA进行术前、术中及术后血 AT- 水平检测 ,并与 33例原发性肝癌行肝动脉栓塞 ( TAE)患者治疗前、后的空腹外周静脉、门静脉及肝固有动脉血 AT- 水平进行了比较。结果提示 :TIPS术前的门静脉血 AT- 水平为最高 ,其次是肝静脉、外周静脉、TAE组的外周静脉及肝固有动脉 ( P<0 .0 1 )。肝硬变门脉高压顽固性腹水患者 TIPS术前 AT- 水平较高 ,尤其 TIPS术中肝内门静脉穿刺所取血样 AT- 水平最高 ;而术后的 AT- 水平则明显降低 ,这可能是行
To observe the change in angiotensin Ⅱ(AT-Ⅱ)in chronic hepatic disease pre-and-post interventional therapy, and to determine the reliability of the index of interventional therapy effect, serum AT-Ⅱ levels were analysed by RIA in fifty-six cirrhotic patients with chronic ascites with trans-jugular intrahepatic portosystemic shunt(TIPS)operation, and compared with those of peripheral vein, portal vein and hepatic artery of 33 patients with hepatic cellular carcinoma(HCC)before and after undergoing transcatheter hepatic arterial embolization (TAE). The results showed that AT-Ⅱ leves in portal vein before TIPS were the highest in this study, and then the levels of AT-Ⅱhepatic vein, peripheral vein, the peripheral vein of TAE group and hepatic artery were in fellow( P <0.01). AT-Ⅱ levels of cirrhotic patients with chronic ascites were markedly decreased after TIPS operation and that may be one of cause of the disapperarance of ascites after TIPS operation of the cirrhotic patients with chronic ascites reduce.
出处
《标记免疫分析与临床》
CAS
2001年第2期66-68,共3页
Labeled Immunoassays and Clinical Medicine
关键词
血管紧张素Ⅱ
放射免疫分析
门脉高压
门腔分流
介入放射
肝疾病
Angiotensin Ⅱ
Immunoradiology analysis
Portal hypertension
Portal-systemic shunt
Interventional radiololgy
