摘要
目的:研究养肝胶囊对NK细胞活性的影响。方法:^(137)Cs辐射(2.5Gy)后造成机体的免疫功能下降,NK细胞活性降低。分组:不同剂量灵丹王养肝胶囊10g/kg、58/kg给药组、黄芪组、对照组,分析治疗前后NK细胞水平。结果:不同剂量灵丹王养肝胶囊给药组与黄芪组,其NK细胞水平均比对照组为高,以10g/kg组为最佳,其值接近正常小鼠NK细胞活性水平。经统计学处理与对照组相比,差别有显著意义,而5g/kg组和黄芪组与对照组比,则无统计学意义。结论:灵丹王养肝胶囊能提高^(137)Cs照射(2.5Gy)小鼠的NK细胞活性,而以剂量10g/kg为最佳。
Objevtive: To evaluate the effect of liver-nourishing capsule on the activity of NK cells in mice. Methods: After induced by 2.5Gy 137Cs irradiation, the model mice were randomly devided into four groups of which two were gastrogavaged different dose of liver-nourishing capsule (5. 0g/kg, 10/gkg) for two weeks, two other groups asrragalus and 0. 9% NS control. The activity of NK cells in each groups was investigated. Results: The activity of NK cells in different dose of liver nourishing capsule and asrragalus groups were all higher than 0. 9% NS control. NK cells activity in liver-nourishing capsule high-dose (10. 0g/kg) was higher significantly than 0. 9% NS control (P<0. 05), even close to that in normal mice; while there were no significantly difference in liver-nourishing capslue low dose(5.0g/kg)and asrragalus groups contrasting with NS control. Conclusion: Lingdanwang liver-nourishing capsule could engance the activity of NKcells in 137Cs irradiation mice, the best high dose group.
出处
《中西医结合肝病杂志》
CAS
2001年第3期157-158,共2页
Chinese Journal of Integrated Traditional and Western Medicine on Liver Diseases
关键词
养肝胶囊
NK细胞
动物实验
中成药
药理
Liver-Nourishing Capsule NK Cells Animal Experiment Traditional Chinese Drug
