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后莫紫檀素、美迪紫檀素对人肝癌细胞抑制作用的研究 被引量:9

The inhibitory effects of homopterocarpin and medicarpin on human's liver cancer cells in vitro
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摘要 观察刺果甘草活性成分后莫紫檀素 (homopterocarpin)、美迪紫檀素 (medicarpin)的体外抗癌活性 ,通过人肝癌细胞 (Hep 2 )进行体外实验 ,结果表明它们均有抑制和杀灭人肝癌细胞的作用 ,并且美迪紫檀素的作用强于后莫紫檀素。此 An observation on the anticancer activity of homopterocarpin and medicarpin in vitro,which was separated from the root of Glycyrrhiza pallidiflora Maxim.. The cell culture test was used in these studies in vitro. The experimental result showed that these two ingredients could inhibite(lower concentration) or kill(higher concentration) human's liver cancer cells under the cultured condition, moreover, the effect of medicarpin was stronger than that of homopterocarpin.These two monomers were active components of Glycyrrhiza pallidiflora Maxim.
出处 《沈阳药科大学学报》 CAS CSCD 2001年第3期211-212,共2页 Journal of Shenyang Pharmaceutical University
基金 江苏省教委自然科学基金资助项目!(92 0 89)
关键词 刺果甘草 后莫紫檀素 美迪紫檀素 人肝癌细胞 HEP-2 Glycyrrhiza pallidiflora Maxim. homopterocarpin medicarpin,Hep-2
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参考文献1

  • 1[1]Toplin JA. A tissue culture cytotoxicity test for large-scale cancer chemotherapy screening [J].Cancer Research, 1959,19:959.

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