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肺癌病人手术前后血清脂质唾液酸(LSA)的动态观察

Pre-and Postoperative Sequential Study on the Lipid Sialic Acid of Serum of Patients with Lung Cancer
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摘要 本文报告42例肺癌,30例非癌胸疾病人手术前后血清脂质唾液酸水平的动态变化,并以50例健康人作对照。结果表明:肺癌病人血清脂质唾液酸明显高于非癌胸疾和正常人(P<0.01),其增高的程度与肿瘤病期、原发肿瘤大小,以及淋巴结转移有密切关系,而与组织学类型无关。本实验证明:(1)肺癌病人术后1天血清脂质唾液酸较术前明显升高,术后第7天逐渐降低,术后14天进一步降低,但未能完全恢复至正常水平。(2)非癌胸疾病人术后1天血清脂质唾液酸较术前明显升高,术后14天可恢复到术前水平。 This article presented the serial changes of lipid sialic acid of serum during pre-and postoperative periods in 42 patients with lung cancer and 30 with noncancerous thoracic lesions, and 50 normal adults as a control group. The results of the tests showed that the serum level of lipid sialic acid from patients with lung cancer was significantly higher than that of noncancerous thoracic lesions and normal individuals (P<0.01). The level of LSA was related to the stages of the cancer, the size of primary tumor and the presence of lymph node metastasis, but not to the histological classification. In this study, it was comfirmed. (1) After removal of the tumor, the serun level of LSA of patients with lung cancer was increased remarkably on the 1st postonerative day, and began to decrease to some extent on the 7th postoperative day. It was decreased further on the 14th postoprative day, but did not return to normal level completely. (2) Serum LSA of noncancerous thoracic lesions was increased more significantly on the 1st postoperative day than that before operation and was returned to normal level in 2 weeks after operation.
出处 《华西医学》 CAS 北大核心 1991年第2期198-200,共3页 West China Medical Journal
关键词 肺肿瘤 脂质唾液酸 外科手术 Lung Cancer, Lipid siatic acid, Surgical treatment.
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参考文献3

  • 1周青,张在和,季秀生.肿瘤患者血清中总唾液酸、脂质结合唾液酸和前清蛋白的水平[J]安徽医科大学学报,1988(02).
  • 2阮华业,龙江斌,刘丽梅,邝珠玑,区宝祥,张锋.测定血清脂质结合唾液酸浓度检测癌症[J]癌症,1987(05).
  • 3陈书盘,郭虹,蔡钦.定量测定血清脂质结合唾液酸诊断肺癌[J].上海医学,1983(5):263-265. 被引量:9

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