摘要
对60例婴幼儿急性肺炎中29例采用精制α型人白细胞干扰素加抗生素治疗(治疗组,其中病毒性肺炎15例),以单用抗生素治疗的31例作对照(其中病毒性肺炎16例)。结果显示,病毒性肺炎治疗组较对照组的临床表现消失时间缩短1.4～2.8天,临床治愈及痊愈时间分别平均缩短1.9天和1.5天。两组间差异有显著性。干扰素治疗前后,淋巴细胞绝对值、T细胞及其亚类以及血清免疫球蛋白含量差异均无显著性,但OKT_3比值略有上升,OKT_3略有下降趋势。
Fifteen cases of viral pneu-monia in infants were treated with refin-ed interferon-α and antibiotics. Clinicalsymptoms of the cases with IFN-α were re-lieved in 1.40-2.79 days, earlier than thoseof the control. Clinical recovery time wason the average shorter than that of thecontrol by 1.9 days,and complete recoveryby 1.5 days. The difference is statisticallysignificant. It suggested that the clinicaleffect of IFN-α together with antibiotics isbetter than that of antibiotics alone. There was no significant change be-tween the experimental and control groupsin absolute lymphocyte count Ig and T-cell,but OKT_3 increased and OKT_3 decreasedslightly. The study shows that IFN is an effec-tive and safe administration for viralpneumonia.
出处
《华西医科大学学报》
CSCD
1991年第4期420-423,共4页
Journal of West China University of Medical Sciences
关键词
婴幼儿
病毒性
肺炎
干扰素
Interferon
Viral pneumonia
Immunoglobulin
T-cell
