摘要
目的进一步探讨超声引导下离子加速电化学治疗肝癌的可行性和疗效。方法13例晚期肝癌患者进行超声引导下离子加速电化学治疗 ,术中电压6～9伏特 ,电流50～70毫安 ,治疗时肿瘤内注入5 %盐水2ml+卡铂100～200mg。结果CR(完全缓解)5例(38.5%) ,PR(部分缓解)4例(30.7 %) ,有效率(CR +PR)69.2%。一年生存率为84.6%(11/13) ,三年生存率38.5 %(5/13) ,五年生存率7.7 %(1/13)。结论超声引导下离子加速电化学治疗是一种安全、有效的治疗方法 ,尤其适合于中晚期肝癌和转移性肝癌。
Objective To evaluate the efficacy of electrochemotherapy(EChT) combined with ion acceleration in patients with advanced liver cancer under Ultrasound guidance. Methods 13 patients with advanced liver cancer were treated by EChT under ultrasound guidance. Voltage was 6.0～9.0V and current was 50～70mA. 5% NaCl 2ml plus DDP100～200mg was injected into the tumor. Results The curative rate was 69.2%(9/13) with 5(38.5%) in completely relaxed and 4(30.7%) in partially relaxed. The survival rates for 1,3 and 5 years was 84.6%(11/13)?38.5%(5/13) and 7.7%(1/13), respectively. Conclusion EChT combined with ion acceleration under ultrasonography is simple and effective in treating intermediate or advanced liver cancer.
关键词
超声引导
离子加速电化学治疗
肝癌
晚期
Ultrasonography Ion accelerated electrochemical therapy Liver cancer
