摘要
取食管癌高发区139例食管拉网涂片,以改良邹氏法进行γ-GT活性测定。结果,正常涂片中17.5％(11/63)为γ-GT阳性;轻度增生涂片中32.6%(15/46)为γ-GT阳性;重度增生Ⅰ级涂片中36%(9/25)为γ-GT阳性;重度增生Ⅱ级涂片中100%(2/2)为γ-GT阳性;有癌细胞涂片中100%(3/3)为γ-GT阳性。对非癌细胞而γ-GT呈阳性反应的细胞,证明其已产生癌样代谢改变。对这类病人应定期随访,以便发现早期癌。
γ-Glutamyl transpeptidase(γ-GT) activity of the cells from esophageal abrasive balloon cytocollection in 139 cases from the high incidence area of esophageal cancer was detected by the improved Zhou's method. The γ-GT positive cells may be 17.5%(11/63) in normal smears; 32.6%(15/46) in dysplastic smears; 36%(9/25) in 1-degree hyperplastic smears; 100%(2/2) in 2-degree hyperplastic smears; 100%(3/3) in squamous cancer-cell smears. The γ-GT positive changes in the non cancer cells have proved the occurance of the cancer-like metabolic change; regular examination of the patients should be done so as to discover the early stage of esophageal cancer.
出处
《河南肿瘤学杂志》
1991年第1期17-19,共3页
Henan Journal of Oncology
关键词
食管癌
Γ-GT
组织化学
esophageal cancer
γ-glutamyl transpeptidase
histochernistry
