摘要
目的为尽快降低食管癌高发区的癌发病率，寻找防治的突破口。方法对４５１例高危人群的内镜刷片作γＧＴ检测，并与活检标本的病理检查结果相对照。结果发现一年前的４０岁以上高危人群中食管癌发病率随年龄逐渐升高。在所检测到的癌患者中，除未能进行γＧＴ检测者外，所有癌患者的刷片γＧＴ皆呈阳性反应。结论重增同时伴有γＧＴ阳性反应的患者应视为高癌变风险人群，应对其积极防治和追踪观察，从而使食管癌的防治对象更加准确，防治措施更加有效。
Abstract Aim To quickly decrease the frequency of esophageal cancer in the high
incidence area and find the way to prevent and treat this disease. Method GT detection was
carried out on the endoscopic mucosa smears from 451 cases of severe hyperplastic
esophageal mucous membranes,and compared the results with the biopsies and pathological
findings. Result The frequency of esophageal cancer of the high risk subjects above 40
gradually increased with age,the results of GT reaction showed positive reaction in all detected
individuals with cancer. Conclusion The subjects with both severe atypical hyperplasia and
positive GT reaction should be regarded as high risk population of canceration,active
prevention and treatment and followup examinations should be taken,so that the subjects would
be more accurate and the measures would be more effective.
出处
《胃肠病学和肝病学杂志》
CAS
1999年第2期103-104,共2页
Chinese Journal of Gastroenterology and Hepatology
基金
国家自然科学基金
