摘要
目的 探讨急性肾炎患儿治疗前后外周血 B细胞和 T细胞亚群含量。方法 应用单克隆抗体技术测定 30例小儿急性肾炎外周血 B细胞和 T细胞亚群 ,并以 35名健康人作对照。结果 急性肾炎患儿外周血 B细胞数显著地高于正常对照组 (P<0 .0 1) ,CD3、CD4、CD4/CD8显著地低于正常人对照组 (P<0 .0 1或 P<0 .0 0 1)。结论 急性肾炎患儿为一种自身免疫调节异常的疾病。
Objective To explore the content of B lymphocyte and T lymphocyte subgroups in periperal blood in children with acute nephritis pre and post therapy.Methods Immunological technique was used to detect B and T as well as T subgroups of lymphocyes in pheripheral blood in patients with acute nephritis compared with 35 healthy controls.Results B lymphocytes were extremely higher than those in normal control( P <0.01),but CD 3、CD 4 and the ratio of CD 4/CD 8 were obviously lower( P <0.01 or P <0.001).Conclusion Acute nephritis is a kind of disease due to abnormal immunoregulation.
出处
《淮海医药》
2001年第2期108-109,共2页
Journal of Huaihai Medicine
