摘要
目的 :观察针刺治疗对 型糖尿病并发急性脑梗死 (ACI)时免疫细胞因子的影响 ,以探讨其作用机制。方法 :将 6 0例患者随机分为常规药物组 (对照组 30例 )与常规药物加针刺治疗组 (治疗组 30例 )进行对比观察 ;用放射免疫分析法 (RIA)分别对 2组患者治疗前后白介素 6 (IL 6 )及肿瘤坏死因子α(TNFα)水平进行检测 ,并与健康人组作比较。结果 :患者入院时 IL 6及 TNFα水平显著升高 ,与健康人组比较有非常显著性差异 (P<0 .0 0 1) ;治疗后 ,2组免疫细胞因子含量均明显降低 (P<0 .0 1和 P<0 .0 0 1) ,且针药联合治疗组下降幅度较单纯常规药物对照组更大 (P<0 .0 5 )。结论 :针刺可改善 型糖尿病并发 ACI患者的免疫病理反应 。
Objective:To observe the influence of acuptreatment on immune cell factors and investigate the potential mechanisms in type Ⅱ diabetic patients complicated with acute cerebral infarction(ACI).Methods:Sixty cases were randomly divided into 2 groups.The control group (n=30) was treated with conventional therapy alone,but the treatment group (n=30) with conventional therapy as well as acupuncture.The plasma levels of interleukin6(IL6) and tumor necrosis factorα(TNFα) before and after treatment were measured by radioimmunoassay (RIA) method and compared with healthy subject group.Results:It showed that the levels of plasma IL6 and TNFα were very significantly increased when admitted in comparison with healthy subject group (P<0.001);their contents were markedly reduced after acuptreatment(P<0.01 and P<0.001).Conclusions:The results suggest that acuptherapy be able to improve immune pathologic response in type Ⅱ diabetic patients complicated with ACI,these changes might be a potential mechanisms through regulating functional disorder of neurotic endocrinal immune network (NEIN) following stroke.
出处
《中国中西医结合急救杂志》
CAS
2001年第2期92-94,共3页
Chinese Journal of Integrated Traditional and Western Medicine in Intensive and Critical Care
基金
广东省中医药管理局科研基金资助项目!(No.199845 5 )
