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老年不稳定型心绞痛患者血浆D-二聚体检测的临床意义 被引量:1

THE CLINICAL SIGNIFICANCE OF DETERMINATION OF D-DIMER IN PLASMA IN ELDER PATIENTS WITH UNSTABLE ANGINA PECTORIS
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摘要 为探讨高龄不稳定型心绞痛 (UAP)患者血浆D 二聚体水平检测的临床意义 ,选择 70岁以上心绞痛患者 5 0例 ,其中UAP 2 8例 ,稳定型心绞痛 (SAP) 2 2例 ;健康对照 16例。采用Latex半定量法测定血浆D 二聚体及血清纤维蛋白降解产物 (FDP)水平。结果显示 :UAP组血浆D 二聚体阳性率 (2 0 / 2 8)较健康组 (1/ 16 )和SAP组 (3/ 2 2 )显著增高 ,UAP组血清FDP阳性率与SAP组无显著差异。提示血浆D 二聚体阳性是高龄UAP患者的特征 ,对D To investigate the clinical implication of the detection of plasma D-dimer level in elderly UAP patients, 50 patients with angina pectoris and 16 normal health volunteers were selected for this study.D-dimer and fibrin degradation products (FDP) were determined by the half-quantity Latex method.The positive rate for D-dimer was markedly higher in UAP group(20/28) than in SAP group(3/22) and healthy group(1/16).The positive rate for FDP showed no significant difference between UAP group and SAP group.It suggested that higher plasma D-dimer level was one of the charictaristics in elderly patients with UAP.For an elderly patient,if the plasma D-dimer is strongly positive, administration of low doses of thrombolytic agent may be considered.
出处 《解放军医学杂志》 CAS CSCD 北大核心 2001年第4期254-255,共2页 Medical Journal of Chinese People's Liberation Army
关键词 D-二聚体 不稳定型心绞痛 老年医学 血浆 D-dimer angina,unstable geriatrics
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