摘要
目的 :为了解皮肌炎患者医院感染的发生情况及其对预后的影响。方法 :对 6 2例皮肌炎有住院患者进行回顾性调查、分析、总结。结果 :6 2例皮肌炎患者并发医院感染 2 6例 ,感染率为 41.9% ,医院感染率随住院时间和使用激素及免疫抑制剂的时间延长而呈增高趋势。激素及免疫抑制剂联合应用医院感染率达 6 0 .0 % ,与单独应用激素者医院感染率 2 9.7% ,有明显差异 (P <0 .0 5 )。感染部位以呼吸道、胃肠道、皮肤软组织占前3位。医院感染的致病菌共检出 2 1株 ,其中革兰氏阴性杆菌 10株 (4 7.6 % ) ,革兰氏阳性球菌 5株 (2 3.8% ) ,真菌 6株 (2 8.6 % )。发生医院感染后的病死率 (34 .6 % )与无医院感染者的病死率 (11.1% )相比也具有显著性差异 (P <0 .0 5 )。结论 :皮肌炎患者易并发医院感染 。
Objective:In order to understand the nosocomial infection of dermatomysitis and the influence to the follow up.Methods:62 cases hospitalized were investigated and analyzed retrospectively.Results:In 62 cases of dermatomysitis,there wrer 26 cases complicated by nosocomial infection,the rate of nosocomial infection was 41.9%.The rate tended to rise with the lenghthen of the time of hospitalization and the usage of corticosteroid as well as immunonodepressives.The infection rate of the cases treated with corticosteroid combined with immunodepressives reached 60.0%.Compared with the infection rate(29.7%) of the cases treated with the corticosteroid singly(P<0.05).The three foremost in the infection site were respiratory tract,gastrointestinal tract and skin soft tissue.21 strains of the pathogenetic baceria of the nosocomial infection were found.Among which there were 10 Grma-negative bacilli strains (47.6%),5 Gram-positive coccus strains (23.8%),6 fungi strains (28.6%).Compared to the mortality rate (11.1%) of non nosocomial infection,the mortality rate (34.6%) of with the nosocomial infection was significance (P<0.05).Conclusions:The cases of dermatoystis is apt to be complicated by various nosocomial infection and the infection affected the prognosis.
出处
《中国现代医学杂志》
CAS
CSCD
2001年第3期45-46,共2页
China Journal of Modern Medicine
关键词
皮肌炎
医院内感染
预后
Dermatomystis
Noscomial Infection
