摘要
为了解皮肌炎患者的预后，１９９５年６月～９月，上海市皮肌炎医疗协作中心调查了１１９例皮肌炎患者，并对１０项预后因素进行ＬｉｆｅｒｅｇＰｒｏｃｅｄｕｒｅ多因素分析。结果表明：其２年及５年的生存率分别为７５．３％和５３．２％，肺部感染是最常见的死因，其次是恶性肿瘤。与预后不良有关的因素有：老龄，恶性肿瘤，间质性肺炎，吞咽困难，心脏累及，发热，病情不能缓解，单用激素治疗。生存曲线还显示：发病后３年内死亡幅度较大，３～７年间死亡幅度较小，７年以后无病人死亡。该结果提示：皮肌炎预后不良，其预后受多种因素影响，应尽早、正规给予激素和免疫抑制剂治疗。
In order to know the prognosis of dermatomyositis, 119 patients with dermatomyositis were investigated from June to September 1995 by Shanghai Medical Cooperation Center on Dermatomyositis. Ten prognostic factors were studied with Lifereg Procedure multiple factor analysis. The results showed that 2 and 5 year survival rates were 75.3% and 53.2% respectively. The most common cause of death was lung infection and then was malignant tumor. Unfavorable prognostic factors were old age, malignant tumor, interstitial lung disease, dysphagia, cardiac involvement, fever, failure of remission and steroid therapy alone. The survival curve showed that mortality rate was high in the first three years, less between three and seven years and none after seven years. The results showed that dermatomyositis is a disease with poor prognosis. Patients with dermatomyositis can be adversely affected by many factors and should be treated regularly with steroid and immunosuppresive drugs as early as possible.
出处
《中华内科杂志》
CAS
CSCD
北大核心
1997年第1期32-35,共4页
Chinese Journal of Internal Medicine
