摘要
目的 探讨直肠癌区域淋巴结转移规律及术中判断淋巴结转移的准确性。方法 回顾性分析 180例根治性手术后的直肠癌临床资料 ,分析淋巴结转移情况。结果 患者的性别、年龄和肿瘤的大小与淋巴结转移无明显关系 ,肿瘤浸润肠壁的深度及肿瘤的分化程度与淋巴结转移有关。T3～T4 时 ,其淋巴结阳性率和转移度显著高于T1～T2 者 (P<0 0 5 ) ,低分化肿瘤的淋巴结阳性率和转移度明显高于高分化肿瘤 (P <0 0 5 )。 5 1例术中发现淋巴结肿大 ,12 9例未发现淋巴结肿大 ,术后病理证实分别有 31例和 77例淋巴结转移阳性。结论 直肠癌淋巴结转移与肿瘤浸润肠壁的深度及分化程度有关 ,手术中淋巴结是否转移不准确 。
Objective To study the rule of lymph node metastases in rectal cancer patient and the accuracy of judgment of lymph node metastases during operation.Methods To analyse retrospectively the clinical materials of 180 patients who had received radical surgery of rectal cancer. Results Lymph node metastases were found in 108 of 180 treated patients (60 %) 2173 lymph nodes dissected, metastases existed in 207 (9 5 %). Tumor differentiation and the depth of tumor invasion were factors influencing lymph node metastases, but the patients's sex, age and the size of the tumor were not. Lymph node positive rate and ratio of number of invaded to removed lymph node in T 3 and T 4 patients were higher than that in T 1 and T 2 patients ( P <0 05). Lymph node positive rate and ratio of number of invaded to removed lymph node in poorly differentiated tumor were higher than that in well differentiated tumor ( P <0 05). Lymph node positive rate in 51 patients with palpable lymph nodes and 129 patients without palpable lymph nodes were 60 8% and 59 7% respectively. Conclusion Lymph node metastasis of rectal cancer is related with depth of tumor invasion and differentiation of the tumor cells. Whether or not lymph nodes were palpable or enlarged during operation cannot be regarded as a reliable judgement of metastasis. Routine lymph node cleaning is necessary.
出处
《肿瘤》
CAS
CSCD
北大核心
2001年第2期120-121,共2页
Tumor
