摘要
目的探讨大肠癌淋巴结转移的相关因素,为临床诊断和治疗提供参考。方法对我院2000至2001年施行根治手术治疗的345例大肠癌的资料进行分类整理,用χ2检验及Logistic多因素回归分析各临床病理因素与淋巴结转移的关系。结果大肠癌淋巴结转移率、转移度与患者性别、肿瘤部位等无明显关系,而与浸润深度、淋巴管浸润、大体类型、组织学分级等有关。Logistic多因素回归分析表明,相关因素与淋巴结转移的相关程度依次为:肿瘤浸润深度、淋巴管浸润、大体类型、组织学分级、肿瘤类型、肿瘤大小。结论大肠癌淋巴结转移相关因素:浸润深度>淋巴管浸润,是影响淋巴结转移的最重要因素。
Objective To investigate the factois related to lymph node metastasis of colorectal car- cinoma, in order to provide reference for clinical diagnosis and treatment. Methods A retrospective analysis was performed in the 345 patients with colorectal carcinoma who had underwent radical resection from 2000 to 2001 in our hospital. The relations between lymph node metastasis and clinicopathologic variables were evaluated by Chi-square test and logistic regression. Results Lymph node metastasis rate and ratio of number of invated to removed lymph node （I/R） in colorectal cancer were not related to patient＇s sex and the site of the tumor, but related to depth of tumor invasion, lymphatic invasion, macroscopic type and differen- tiation of the tumor. Multivariate logistic regression analysis showed that the degree of lymph node metastases was related to depth of tumor invasion, lymphatic invasion, macroscopic type, differentiation of the tumor, pathological type and tumor size. Conclusion Lymph node metastases of colorectal carcinoma is related to depth of tumor invasion and lymphatic invasion and the depth of tumor invasion is the major factor.
出处
《中国肿瘤临床与康复》
2008年第2期106-108,共3页
Chinese Journal of Clinical Oncology and Rehabilitation
关键词
结直肠肿瘤
淋巴结阳性率
淋巴结转移度
相关性分析
Colorectal neoplasms
Lymph node positive rate
Ratio of the number of invated to removed lymph node
correlation analysis
