摘要
用10%的香豆素软膏,喷雾剂和粉剂分别对3组Wistar大鼠左后肢急性梗阻性淋巴水肿进行实验治疗。结果表明3种剂型均有疗效,总有效率95.8%,疗效显著者达54.2%,无效1例。其中软膏剂疗效最佳。治疗各组术后32h水肿减轻,水肿肢体由肿胀、灰暗逐渐红润。术后96h皮肤接近正常。
Effect of 10% coumarin in ointment,spray and powder was studied on acute experimental lymphoedema in rat legs.The results showed that the total effective rate was 95.8%,and very obvious effective was 54.2% only one animal was no effective.Ointment among them was the best action the lymphoedema.The oedema of the rat′s legs in the treatment groups was gradually reduced following 24 hours of operation.The skin swollen with marked grey was gradually retured to the rosy.The results of the t-tests of various parameter showed that there was very remarkable statisti-cally significance(P<0.01)in the comparison of treatment groups with the control group.Any side effect was not found in the experiment.Thus,these arc completely suitable to use for clinical application.
出处
《山东医科大学学报》
1991年第4期289-291,共3页
Acta Academiae Medicinae Shandong
