摘要
螺旋藻多糖150~300mg/kg,无论注射或口服,均能提高小鼠腹腔巨噬细胞的吞噬指数,增加外周血液中T淋巴细胞的百分数和血清溶血素的含量。说明螺旋藻多糖不但能提高机体非特异性的细胞免疫功能,而且能促进机体特异性的体液免疫功能。它的作用机理似与螺旋藻多糖能增强骨髓细胞增殖能力,促进胸腺、脾脏等免疫器官的生长和促进血清蛋白的生物合成有关;同时还与其能消除免疫拟制剂(环磷酰胺)对机体免疫系统的抑制作用有关。
Polysacchrides of Spirulina platensis, at the dosage of 150-300 mg/kg by injection or taking orally, can increase the phagocytic percentage and phagocytic index of abdominal macrophage, the percentage of T-lymphocyte and haemolysin content in the peripheral blood of mouse. The results demonstrate the polysacchrides can improve both the non specific function of cellular immunity and the specific humoral immunity. The mechanism seems to be related to the fact that the polysacchrides can enhance the reproductive ability of marr-owcyte, the growth of thymus and spleen, the biosynthesis of serum protein, and that polysacchrides can eliminate the inhibitation effect of inhibitive circlar phosphamide on immune system of body.
出处
《海洋科学》
CAS
CSCD
北大核心
1991年第6期44-49,共6页
Marine Sciences
关键词
螺旋藻
藻
多糖
机体
免疫功能
Polysacchrides, Phagocyte, T-lymphocyte, haemolysin