摘要
目的 :验证大输液生产的管路处理效果。方法 :检测管路经过处理后最终冲洗水中的残留物和微生物指标。结果 :大输液生产的管路按照规定的清洗程序清洗后 ,最终冲洗水的指标如下 :管路进出水口的电导率基本一致 ,菌落数 <50CFU/ml,细菌内毒数 <0 2 5EU/ml。结论
OBJECTIVE:To test and verify the piping cleaning effect in infusion solution productive process.METHODS:Targets of final washing water of pipe were determined.RESULTS:Targets of final washing water of pipe were that electrical conductivity of entrance of pipe was equal to that of exit of pipe essentially,limitation of bacteria and endotoxin were as follows:<50CFU/ml,<0.25EU/ml.CONCLUSIONS:According to the clean rules laid down by pharmaceutical Factory of Shanquan,the desired cleaning effect of the pipe of infusion solution can be achieved.
出处
《药学实践杂志》
CAS
2001年第2期83-85,共3页
Journal of Pharmaceutical Practice
