摘要
目的探讨人体在不同运动状态下血清中活性氧 (ROS)及其清除体系中还原型谷胱甘肽 (GSH)、谷胱甘肽过氧化物酶 (GSH－ PX)的变化特征。方法应用跑台提供运动负荷，进行安静状态时、亚极量负荷和力竭性运动后有关指标的测定。结果血清中 ROS亚极量负荷后显著高于安静时，力竭性运动后又显著高于亚极量负荷时 (P< 0.001)； GSH含量和 GSH－ PX活性亚极量负荷后显著降低 (P< 0.001)，力竭性运动后回升，但仍低于安静时水平。结论 ROS随运动强度的加大和时间的延长而明显升高， GSH含量和 GSH－ PX活性则呈现出先显著下降随后再回升的趋势。
∶ Objective To probe the alterated characteristic of reactive oxygen species,reduce glutathione and glutathione peroxidase(GSH－ PX) in serum of persons.Method Under the controlled load by treadmill,correlative indexes were determined during resting state,sub－ maximal load and exhaustive exercise.Result ROS level of serum increased significantly during sub－ maximal load compaired with that of resting state.The ROS level during exhaustive exercise was higher than that of sub－ maximal load(P<0.01).GSH content and GSH－ PX activity decreased significantly(P<0.001).GSH content and GSH－ PX reactivity decreased significantly(P<0.001)during sub－ maxiaml load and increased after exhaustive exercise which was still lower that of resting state.Conclusion ROS increased with the enhancement of exercise intensity and the time.GSH and GSH－ PX showed a significant decrease in content and activity respectively followed by apparent enhancement.
出处
《现代康复》
CSCD
2001年第3期57-58,共2页
Modern Rehabilitation
