摘要
目的 通过研究生殖器疱疹（ＧＨ）患者发作期病毒活力的强弱与间歇期是否有活病毒排出，探讨其传染活性。方法应用非洲猴肾细胞（Ｖｅｒｏ）对 ８２例 ＧＨ患者泌尿生殖道标本进行单纯疱疹病毒（ＨＳＶ）分离培养。通过观察Ｖｅｒｏ细胞受感染的病变程度，将其分为四级。结果 ８２例 ＧＨ患者中 ４４例 ＨＳＶ阳性；水疱期强阳性明显高于糜烂、结痂期。三者之间有高度显著性差异（Ｐ＜０．０１）。结论ＧＨ发作期的皮疹内病毒含量多，感染活力强。特别是发作２天内的皮疹传染性高。
Objective In order to evaluate the infectious ability of patients with genital herpes(GH) in different phase, cell pathogenesised effection(CPE) in Vero cell producted by HSV was studied. Methods 82 samples obtained from patients with GH and patients had history of GH,specimens were cultured to isolated HSV. Positive result was divided into four grades accord- ing to CPE cell number after incubation. Results Among 82 samples, 44 were HSV positive. Positive rate in vesicle phase was significantly stronger than that of erosion phase and crust phase(P< 0. 01 ). Conclusion Eruption of vesicle and within less than two days the patient may have stronger transmission ability, the cause is a great deal HSV inclusion in vesicle or early lesion.
出处
《中国皮肤性病学杂志》
CAS
北大核心
2001年第2期88-89,共2页
The Chinese Journal of Dermatovenereology
基金
广东省卫生厅科研基金资助项目内容
