摘要
对海拔４０８０ｍ地区病毒性肝炎患者的红细胞──超氧化物岐化酶（ＳＯＤ）和血清丙二醛（ＭＤＡ）的含量进行了测定，其结果与本地健康人进行了对比，患者ＳＯＤ含量明显低于对照组（Ｐ＜０．０１），ＭＤＡ含量明显高于对照组（Ｐ＜０．０１），有非常显著差异。揭示自由基在病毒性肝炎的发病机制中起着重要作用。高原地区病毒性肝炎患者由于长期组织缺氧造成肝细胞进一步损害，使体内氧自由基增多，因此，高原地区在治疗病毒性肝炎时给予自由基清除剂和抗氧化剂是十分有益的。
The level of superoxide dismutase(SOD)and malondialdehyde(MDA)were
measured in pa-tients with viral hepatitis at 4 080m altitude.The
results showed that the SOD decreased andMDA increased significantly.
It was suggested oxygen free radicals(OFR)might ply an importantrole
in the pathogenesis of viral hepatitis,The liver cells of patients
were damaged due to serioustissue deoxygenation at high altitude,so
the OFR were increased.It might be profitable to usemedicne of
cleaning OFR aid antioxygenation in vital hepatitis
出处
《高原医学杂志》
CAS
1995年第1期42-43,共2页
Journal of High Altitude Medicine
关键词
海拔
病毒性肝炎
超氧化物峻化酶
丙二醛
high
altitude
viral hepatitis
superoxide dismutase
malondialdehyde
