摘要
近年来,耗散型石英晶体微天平(QCM-D)技术已经广泛用于细胞黏附行为的实时动态监测与研究,细菌生物膜(BBF)因其在临床治疗、食品工业、船体腐蚀和水环境污染等诸多领域给人类社会带来严重危害,造成巨大经济损失而备受关注。文章综述了近3年来将QCM-D技术应用于BBF研究的最新进展,主要包括BBF形成过程的动态监测与动力学信息分析;BBF形成过程的影响因素与生长参数研究;与其他分析技术结合,对BBF形成过程与性质的定性定量研究等。该研究可以进行动态、无损、实时的BBF生长研究,特别是进行BBF的生长动力学分析,但对于量化分析还需结合其他技术手段。
In resent years QCM--D has been used to study cell adhesive behaviors in real--time. Bacteria Bio--Film has also been fo- cused because of its wide and huge influence on medical, food, technology, military and environmental fields. This paper reviewed the study on BBF using QCM--D technology in recent 3 years, including the dynamic study on the formation process of BBF, the in- fluent factors study in the formation of BBF, combination with other analysis technologies, study BBF property qualitatively and quantitatively. QCM--D gave a novel insight to study BBF in real--time, non--invasive method, even the mechanic information on BBF formation. Other technology was needed to analysis on BBF formation using QCM--D punitively.
出处
《重庆师范大学学报（自然科学版）》
CAS
CSCD
北大核心
2014年第4期136-140,共5页
Journal of Chongqing Normal University:Natural Science
基金
国家自然科学基金(No.31070830)
重庆市自然科学基金(No.CSTC2012jjA1501)
