摘要
目的评价颈动脉超声射频信号内中膜厚度定量分析（QIMT）与动脉硬度定量分析（QAS）技术在不同测量方法下的可重复水平。方法招募30例健康志愿者接受颈动脉QIMT／QAS检查。测量指标包括QIMT的内中膜厚度（IMT）与QAS的扩张系数（Dc）、顺应系数（CC）、硬度指数α（α）、硬度指数β（β）及脉搏波传导速度（PWV）。测量方法包括“单侧／单次”、“双侧／双次”、“单侧／双次”。于观察者内及观察者间进行可重复性研究，比较不同QIMT／QAS指标及测量方法的可重复性水平。结果QIMT／QAS具有极高水平的观察者内可重复性（ICC〉0．8）。QIMT在不同测量方法下，观察者间均具有极高水平的可重复性（ICC〉0．8）。对于QAS，各弹性指标的观察者间可重复性水平依次为PWV〉β≈α〉CC〉DC；各测量方法的观察者间可重复性水平依次为“单侧／双次”〉“双侧／双次”〉“单侧／单次”。结论QIMT技术具有极高水平的可重复性。QAS的观察者间可重复性水平因弹性指标和测量方法而异。其中DC与“单侧／单次”的可重复性水平较差，不推荐使用。
Objective To evaluate the reproducibility of quality intima-media thickness（QIMT） and quality arterial stiffness （QAS） technique in assessment of carotid under different measuring methods. Methods Between December 2012 and January 2014,carotid QIMT and QAS examinations were carried out in 30 health volunteers. QIMT and QAS indicators included IMT in QIMT and distensibility coefficient （DC） ,compliance coefficient（CC）, stiffness index α（α）, stiffness index β（β）, pulse wave velocity（PWV） in QAS. The measurement employed ＂unilateral/once＂, ＂bilateral/twice＂, and ＂unilateral/twice＂ methods. Using intra-observer and inter-observer variability, the reproducibility was compared between different QIMT and QAS indicators and measuring methods. Results Extremely high level of intra-observer reproducibility was found for both QIMT and QAS technique （ICC〉0.8）.QIMT also showed an excellent inter-observer reproducibility （ICC 〉 0.8）. In contrast, the reproducibility of QAS technique varied in different indicators （ PWV 〉 β ≈ α〉 CC 〉 DC） and method （＂ unilateral/once＂ 〉＂ bilateral/twice＂ 〉＂ unilateral/twice＂）.Conclusions QIMT measurement was highly reproducible.Whereas the reproducibility of QAS technique varied in different indicators and methods.Due to low reproducibility,the study result did not support the clinical application of DC indicator and ＂unilateral/once＂ method.
出处
《中华超声影像学杂志》
CSCD
北大核心
2014年第6期484-488,共5页
Chinese Journal of Ultrasonography
关键词
超声检查
颈动脉
内膜中膜厚度
结果可重复性
Ultrasonography
Carotid arteries
Carotid intima-media thickness
Reproducibility of results
