摘要
人参是在世界范围内广泛应用的传统中药,其最主要的活性成分为人参皂甙,主要包括Rb1、Rb2、Rc、Rg1等单体。研究发现,人参皂甙对心血管系统具有良好的保护作用,它可以通过抑制凋亡和自噬、抗氧自由基、减轻钙超载、抑制中性粒细胞激活和炎症介质释放、以及参与新生血管形成等一系列多因素,多途径的调节过程,改善缺血心肌功能。
Ginseng is one of the most popular traditional Chinese medicine which has been widely used all over the world. Ginsenoside, a major bioactive component of ginseng, has various beneficial effects on the cardiovascular system. The potential mechanisms of Ginsenoside include resistance to apoptosis and autophagy, reducing oxidative stress, inhibiting calcium overload, the inhibitory effect of neutrophil activation and enhancing angiogenesis.
出处
《中国分子心脏病学杂志》
CAS
2014年第3期974-977,共4页
Molecular Cardiology of China
基金
国家自然科学基金(81070169
81170129)
关键词
人参皂甙
缺血心肌
保护作用
保护机制
Ginsenoside
Ischemic Myocardium
Protective Effect
Protection Mechanism
