摘要
目的探讨冠心病老年患者经皮冠状动脉介入术（PCI）后发生支架内再狭窄（ISR）的危险因素。方法选取我院住院行PCI术老年患者418例，年龄60～79岁，平均（71．3±8．9）岁，男性262例，女性156例。收集所有患者可能的PCI术后ISR危险因素进行统计学分析。结果PCI后1年复查，418例中ISR组104例（24．9％）、非ISR组314例（75．1％）。Logistic回归分析结果显示，年龄、性别与ISR发生率无相关性（P〉0．05）；体质指数（OR=9．54，95％CI：6．542～32．154，P=0．002）和吸烟（OR=26．01，95％CI：5．532～122．238，P=0．000）、高血压（OR=15．72，95％CI：3．24076．026，P=0．001）、糖尿病（OR=11．98，95％CI：2．667～53．835，P=0．001）、高脂血症史（OR=8．98，95％CI：2．164～37．283，P=0．003）及锻炼时间（OR=5．63，8，95％CI：2．004～25．385，P=0．013）与术后ISR呈正相关。结论控制吸烟、高血压、糖尿病、高脂血症等危险因素，适当运动、控制体质量可防止老年患者PCI后的ISR。
Objective To explore the risk factors for in-stent stenosis （ISR） in coronary artery disease in elderly patients undergoing postoperative percutaneous coronary intervention （PCI）. Methods We chose 418 cases undergoing PCI in our hospital. There were 263 males and 156 females, aged from 60 to 79 years, average （71.3 ± 8.9）years in this study. Under the same conditions of treatment strategies, we collected all possible risk factors for ISR in patients undergoing postoperative PCI, and statistics were analyzed. Results All patients were rechecked at 1 year after PCI. 104 cases （24.9%） occurred ISR, and 314 cases （75.1%） were diagnosed without ISR. Multiple logistic analysis showed that, and sex had little effect on 1SR incidence （P〉0.05）. Body mass index（OR=9. 54,95% CI：6. 542-32. 154, P=0. 002）, smoking history（OR= 26.01,95% CI：5. 532-122. 238, P= 0. 000）, hypertension（OR= 15.72,95% CI： 3. 240-76. 026, P=0. 001）, diabetes mellitus（ OR= 11. 98,95%CI2. 667-53. 835, P= 0. 001） , history of high cholesterol（ OR= 8. 98,8,95%0CI2.164 37. 283, P=0. 003 ）, exercise time （ OR = 5. 63,8,95 % CI2. 004 - 25. 385, P = 0. 013 ） had positive correlations with ISR incidence . Conclusions Effective control of risk factors including smoking, hypertension, diabetes, high cholesterol, proper exercise, and weight control can help prevent the development of ISR in elderly patients with postoperative PCI.
出处
《中华老年医学杂志》
CAS
CSCD
北大核心
2014年第6期591-593,共3页
Chinese Journal of Geriatrics
