摘要
随着经济的迅猛发展和人们生活水平的日益提高,高脂血症已经成为不容忽视的问题,其中高甘油三酯血症也是动脉粥样硬化的重要影响因素。目前临床降胆固醇的药物很多,降甘油三酯的药物相对较少;并且降甘油三酯的药物以贝特类和烟酸类药物居多,而中成药较少,文章综述了近年来国内外学者在中草药抗高甘油三酯血症方面的研究进展及相关的作用机制,分析了从天然产物中寻找和发现有价值的药效成份的应用前景,为抗高甘油三酯血症药物的研究与开发提供参考。
Objective：Hyperlipidemia has become an issue which can not be ignored, with the rapid development of economy and peopleh living standards rising, where hypertriglyceridemia is an important factor of atheresclerosis. Therei-e many Clinical lipid-lowering drug, and the ma- jority are cholesterol-lowering drugs, the number of triglycerides-lowering drugs is relatively small; the most of triglyceride-lowering drugs are western medicine. However, Chinese patent drugs are fewer which are only limited to several drugs, such as fibrates and niacin. This paper reviews the research progress, mechanism and the health benefits of Chinese herbal and analyzes the application prospects of discovering valuable pharmacodynamic ingredients from natural products , which provides a reference to the research and development of anti-hypertriglyceridemia drugs.
出处
《中药药理与临床》
CAS
CSCD
北大核心
2014年第1期142-146,共5页
Pharmacology and Clinics of Chinese Materia Medica
基金
科技部"重大新药创制"专项-创新药物研究开发技术平台建设-中药药效学及安全性评价(2012ZX09301002-001-026)
