摘要
本文研究了甲壳质衍生物 916对 H2 O2 损伤的淋巴细胞的保护作用。在造模的同时 ,分别给药 0 .0 0 1～ 10 0 mg· L-1,作用 2 h后用 MTT法检测细胞的存活率。结果显示 ,916在浓度为 0 .0 0 1～ 10 0 mg· L-1范围内皆可对抗 12 .5μmol· L-1H2 O2 造成的淋巴细胞损伤 ,明显升高淋巴细胞的存活率 ,并且呈剂量依赖关系。结果说明
The protective effect of 916 on lymphocyte damage induced by H 2O 2 was studied in this paper. Exposure of 916 at given concentrations to lymphocyte was concomitantly incubated with H 2O 2 at concentration of 12.5μmol·L -1 . Two hours later, the viable cells were evaluated by MTT assays. The result indicated that 916 exerted significant protective effect on lymphocyte from injury, indicating a potent antioxidant activity.
出处
《中国海洋药物》
CAS
CSCD
2001年第1期25-27,共3页
Chinese Journal of Marine Drugs
