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营养支持与早产儿宫外生长迟缓关系的研究 被引量:11

Study on the relationship between nutritional support and extrauterine growth retardation of premature infants
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摘要 目的:通过观察早产儿住院期间营养支持与体重增长的变化,探索营养支持与早产儿宫外生长迟缓(EUGR)的关系,为制定早产儿的营养支持策略提供依据。方法:将2010年2月-2012年3月沈阳市儿童医院新生儿科重症监护病房收治的154例早产儿按出院体重及出院胎龄的关系分为EUGR组和非EUGR组(对照组),分析住院期间患儿体重增长情况,探索营养支持因素与EUGR的关系。结果:出院时发生EUGR的早产儿其出生体重明显低于对照组,住院时间、生理性体重恢复时间均长于对照组,差异有统计学意义(P〈0.05);EUGR组的氨基酸和脂肪乳的肠道外静脉营养和开始肠道内营养供给的起始时间均晚于对照组,差异有统计学意义(P〈0.05);EUGR组生后第5天和第15天的热量供给均明显低于对照组,差异有统计学意义(P〈0.05);氨基酸供给在生后第5天差异无统计学意义,但在第15天明显低于对照组,差异有统计学意义(P〈0.05)。结论:低出生体重的早产儿往往由于热量及蛋白质供给的不足,容易造成EUGR,因此对这一部分早产儿采取正确的早期营养支持和及时有效临床治疗,对改善新生儿的生长发育状况意义重大。 Objective:To explore the relationship between nutritional support and extrauterine growth retardation (EUGR) of premature infants by observing nutritional support and the change of body weight of premature infants while in hospital, provide a basis for making nutri- tional support strategies for premature infants. Methods:A total of 154 premature infants treated in NICU of Children's Hospital of Shenyang City from February 2010 to March 2012 were divided into EUGR group and non -EUGR group (control group) according to the relationship between body weight and gestational age when leaving the hospital, the body weight gain of premature infants in hospital was analyzed, and the relationship between nutritional support and EUOR was researched. Results:Birth weight when leaving the hospital in EUGR group was statistically significantly lower than that in control group ( P 〈 0. 05 ) ; the hospitalization time and recovery time of physiological weight in EUGR group were statistically significantly longer than those in control group ( P 〈 0. 05 ) ; the starting times of parenteral nutrition and enteral nutrition in EUGR group were statistically significantly later than those in control group ( P 〈 0. 05 ) ; the energy supports on the fifth day and the fifteenth day after birth in EUGR group were statistically significantly lower than those in control group (P 〈 0. 05 ) ; there was no statistically significant difference in amino acid support on the fifth day after birth between the two groups, but amino acid support on the fifteenth day after birth in EUGR group were statistically significantly lower than those in control group ( P 〈 0. 05 ). Conclusion: EUGR easily occurs in low birth weight premature infants because of lacks of energy and protein ; thus, for these premature infants, correct early nutritional support and timely effective clinical treatment should be taken, which has important significance for improving growth and development of neonates.
出处 《中国妇幼保健》 CAS 北大核心 2014年第17期2718-2720,共3页 Maternal and Child Health Care of China
基金 沈阳医学院科技基金资助〔20122036〕
关键词 早产儿 营养 宫外生长迟缓 相关因素 Premature infant Nutrition Extrauterine growth retardation Relevant factor
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共引文献264

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