摘要
目的探讨单发于鼻腔的神经纤维瘤的临床特点,以提高诊断及治疗水平。方法回顾性分析2例单发于鼻腔的神经纤维瘤的临床资料并复习相关文献。结果 2例患者均因鼻塞就诊,鼻内镜下完整切除肿瘤;术后随访症状缓解,未见肿瘤复发。结论单发于鼻腔的神经纤维瘤少见,免疫组化为确诊手段,首选鼻内镜下手术治疗效果好。
Objective To explore the clinical characteristics of solitary neurofibroma of nasal cavity to improve the diagnosis and treatment level. Methods Clinical data of 2 patients with solitary neurofibroma of nasal cavity was analyzed retrospectively, and related literature was reviewed. Results Of the 2 cases, the tumor was found occasionally in outpatient clinic due to stuffy nose. Soft tissue shadow and uneven enhanced mass were found by enhanced CT scan, with destruction and absorption of surrounding bone. Intraoperative detection showed the boundary of the tumor was clear, and endoscopic total resection was achieved. Pathologic examination showed numerous spindle cells with positive S100 staining. The symptoms got relieved in both cases after operation, and none recurred after 6 months follow-up. Conclusions Peripheral nerve neurofibroma in nasal cavity has been rarely reported in literature. The definite diagnosis depends upon immunohistochemical staining. Total resection is the preferred method for the treatment of this tumor, and endoscopic surgery is the best choice.
出处
《中国耳鼻咽喉颅底外科杂志》
CAS
2014年第2期124-126,共3页
Chinese Journal of Otorhinolaryngology-skull Base Surgery
基金
湖南省医药卫生科研计划项目(C2014-13)
