摘要
目的:探讨神经纤维瘤病(neurofibromatosis,NF)的临床表现、诊断及治疗方法。方法:收集24例神经纤维瘤病患者的临床资料。回顾性分析该病的临床表现、诊断、治疗方法等。结果:24例患者中23例为Ⅰ型神经纤维瘤病(NFⅠ型),均否认家族遗传史。1例为Ⅱ型神经纤维瘤病(NFⅡ型),有家族史。男性14例,女性10例,发病年龄出生至64岁,平均年龄24.7岁。首次就诊20例,复发或再次就诊4例。结论:神经纤维瘤病临床表现多样,对于肿瘤在体表的患者,易于诊断;而肿瘤位于内脏的患者,如何做出准确的诊断,是一个值得探讨的问题。在治疗上,手术达不到根治的目的,术后易复发,需再次手术切除。
Objective ：To discuss clinical manifestation, diagnosis and treatment of neurofibromatosis. Methods ： We collected clinical data of 24 patients with neurofibromatosis. Clinical manifestation, diagnosis and treatment were retrospectively analyzed and review of related literatures were reviewed. Results ： Of 24 cases 23 were neurofibroma- tosis typeⅠ （ NFⅠ） , all of them denied family member had the same disease, 1 patient was neurofibromatosis type Ⅱ（NF Ⅱ ） ,whose family member had the same disease. In these 24 patients, 14 patients were males, others were fe- males, aged from birth to 64 years, and the mean age was 24.7 years. 20 patients were first to consult a doctor, and 4 patients were one more time or relapse. Conclusion ： The clinical manifestation of neurofibromatosis was multiplici- ty. If the tumors on the surface, it was easy to be diagnozed. If the tumors in the internal organs, it was difficult to diagnosis. Operation couldnt get the purpose of cure the disease, because the tumors were easy to relapse after opera- tion.
出处
《现代肿瘤医学》
CAS
2012年第7期1447-1450,共4页
Journal of Modern Oncology
关键词
神经纤维瘤病
诊断
治疗
neurofibromatosis
diagnosis
treatment
