摘要
目的 探讨急性脑梗死患者早期缺血修饰清蛋白和神经元特异性烯醇化酶（NSE）的临床意义.方法 采用终点法和电化学发光法分别对50例入院12 h内的急性脑梗死患者和50例体检健康者血清中的IMA和NSE进行测定.结果 急性脑梗死组血清中IMA的ACB值（56.7±6.10 U/ml）低于对照组（72.55±5.53 U/ml）,差异有统计学意义（t=-13.39,P＜0.01）;急性脑梗死组血清中NSE水平（23.03±6.91 ng/ml）高于对照组（10.85±2.61 ng/ml）,差异有统计学显著性意义（t=11.94,P＜0.01）.结论 IMA可以帮助判断脑组织缺血、缺氧程度,NSE可以帮助判断脑组织受损程度,两者联合检测可以作为急性脑梗死早期诊断、判断疾病缺血和损伤严重程度的指标.
Objective To investigate the clinical significance of acute cerebral infarction in early stage of ischemia modified al- bumin and neuron specific enolase. Methods End-point method and the electrochemical luminescence method were used in patients with acute cerebral infarction in 30 cases within 12 h after admission to hospital and 50 cases of healthy persons in the serum of IMA and NSE were measured. Results Acute cerebral infarction serum IMA values of ACB （56.7 ± 6. 10 U/ ml） was lower than the control group （72.55±5.53 U/ml）,and there was significant difference （t=13.39,P（0.01）. The level of NSE in serum of acute cerebral infarction group （23.03 ±6.91 ng/ml） was higher than the control group （10.85±2.61 ng/ml） ,with significant difference （t= 11.94,P〈0.01）. Conclusion IMA can help to judge the degree of cerebral ischemia,hypoxia,NSE can help to judge the damage of brain. The combined detection can be used to judge the dis ease of ischemia and injury severity index for early diagnosis of acute cerebral infarction.
出处
《现代检验医学杂志》
CAS
2014年第2期121-123,共3页
Journal of Modern Laboratory Medicine
