摘要
目的：通过文献分析,探讨利多卡因发生过敏性休克的特点和规律。方法：检索《中国生物医学文献数据库》（1978~2013年7月）、《中国知网》（1994~2013年7月）和《万方医学网》（1994~2013年7月）有关利多卡因引起过敏性休克的文献资料,针对患者年龄、性别、给药途径、原患疾病、ADR发生时间、临床表现、处理措施、愈后情况、是否有过敏史等进行统计分析。结果：在既往有药物过敏史者中发生率更高;77.38%的患者在用药后5 min内发生过敏性休克。结论：提示临床医生在用药前应仔细询问患者药物过敏史,用药过程应加强观察,全程监护。
Objective： To investigate the features and regularity of anaphylactic shock induced by Lidocaine injection by Chinese literature ananlysis. Methods： Chinese Biological Medical Disc from 1978 to July 2013, China Knowledge Network and Wanfang data from 1994 to July 2013 were retrieved to collect the case reports of anaphylactic shock induced by lidocaine injection. The age, sex, administration route, original disease, occurrence time and clinical symptoms of ADR, treatment measures, recovery and allergic history were statistically analyzed. Results：A higher incidence occurred to patients with drug allergy record, and most of the anaphylactic shock occurred within 5 minutes （77.38%） after administration. Conclusion ：The results suggested that clinical doctors should inquire patient~ allergic history in detail before treatment and carry out their careful observation and strong monitoring during medication.
出处
《药物流行病学杂志》
CAS
2014年第5期329-331,共3页
Chinese Journal of Pharmacoepidemiology
关键词
利多卡因
过敏性休克
文献综述
Lidocaine
Anaphylactic shock
Literature analysis
