摘要
目的：探讨和分析加巴喷丁术后镇痛减少药物使用量的临床疗效，总结其临床价值。方法回顾性分析具有完整临床资料的2012年10月~2013年10月的择期脊柱手术患者34例，分为观察组和对照组，每组患者有17例。两组患者均采用静脉全麻，采用咪唑安定、雷米芬太尼、丙泊酚、罗库溴铵快速诱导，术后连接电子镇痛泵。患者苏醒期如出现烦躁，可给予曲马多50 mg静脉注射，待清醒后拔管。两组患者进行深层组织缝合时均静脉注射曲马多50 mg。观察组患者术前口服加巴喷丁，对照组术前不服用药物。分析和比较两组不同镇痛方法对药物使用量的影响。结果两组患者24 h内曲马多用量具有显著性差异，观察组用药量显著小于对照组，两组VAS（疼痛视觉模拟评分）具有显著性差异，观察组显著优于对照组。结论采用加巴喷丁用于术后镇痛，不仅可以明显减少镇痛药物的用量，增强镇痛效果，降低疼痛评分，具有较好的临床疗效，值得临床借鉴和推广。
Objective To investigate and analyze clinical efficacy of gabapentin on postoperative pain relief and reduction of medicine consumption and summarize their clinical value. Methods Retrospectively analyzing clinical data of 34 patients with spinal operation from October 2012 to October 2013 and dividing them into observation group and control group, 17 patients for each group. Two groups of patients were treated with intravenous anesthesia, using midazolam, remifentanil, propofol, rocuronium induced rapid postoperative analgesia pump connected electronics. Patients wake of such restlessness, tramadol 50 mg may be given intravenously, to be awake extubation. Two groups of patients were intravenous injection of deep tissue suturing tramadol 50 mg. Preoperative oral gabapentin observation group, the control group before surgery without medication. Analyze and compare two different methods on the amount of analgesic drug use. Results The two groups of patients within 24 h tramadol dosage significant differences were observed in treatment group which was significantly lower than control group, two visual analog pain score was a significant difference in the observation group were significantly better than the control group. Conclusion Gabapentin for postoperative analgesia, can not only significantly reduce the amount of pain medication, but also enhance the analgesic effect, reduce pain scores and with better clinical efficacy, so it is worthy of learning and clinical promotion.
出处
《中国现代药物应用》
2014年第10期11-12,共2页
Chinese Journal of Modern Drug Application
关键词
加巴喷丁
镇痛
药物使用量
临床疗效
Gabapentin Analgesia Medicine consumption Clinical effect
