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玉屏风颗粒联合地氯雷他定治疗过敏性鼻炎50例疗效观察 被引量:15

Efficacy of Yupingfeng particles comebined with loratadine in treatment of allergic rhinitis of 50 cases
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摘要 目的:探讨玉屏风颗粒联合地氯雷他定治疗过敏性鼻炎的临床疗效。方法选择2010年1月~2013年1月我院住院治疗的过敏性鼻炎患者100例,根据治疗方法不同随机分为研究组和对照组各50例,对照组予氯雷他定片每次1片口服,每日1次,连用14 d。治疗组同时联合玉屏风颗粒每次1袋冲服,每日3次,连用14 d。比较两组患者治疗后的总有效率及两组患者的喷嚏、鼻塞、流涕、鼻痒的临床症状的缓解时间及随访1个月、2个月后的复发率。结果研究组的总有效率达96.0%,显著高于对照组(P<0.05),且研究组患者的喷嚏、鼻塞、流涕及鼻痒的症状治疗后均较对照组明显缓解(P<0.05)。研究组患者随访1个月和2个月后的复发率明显低于对照组(6.7% vs 27.5%,15.6% vs 37.5%,P<0.05)。结论玉屏风颗粒联合地氯雷他定中西医结合治疗过敏性鼻炎疗效确切,能明显改善患者的临床症状,且无明显不良反应,值得广泛推广和应用。 Objective To investigate the effect of Yupingfeng particles joint desloratadine in treatment of allergic rhinitis. Methods From January 2010 to January 2013 in our hospital, 100 patients with allergic rhinitis according to the methods were randomly divided into study group and control group, 50 patients in the control group was given lo-ratadine tablets each an oral, once a day, once every 14 days. treatment group combined Yupingfeng particles,each bag, blunt, 3 times a day, once every 14 days. Total efficiency and sneezing, nasal congestion , runny nose, itchy nose symp-toms relief time, the recurrence rate after one month, two months of two groups were compared. Results The total effec-tive rate of the study group was 96.0% ,was significantly higher than the symptoms (P 〈0.05), and sneezing, nasal con-gestion, runny nose and nasal itching of study group were relieved more significantly than the control group (P 〈0.05). Study patients were followed up 1 month recurrence rate after two months and were significantly lower than the control group (6.7% vs 27.5%, 15.6% vs 37.5%, P 〈0.05). Conclusion Yupingfeng particles jointly loratadine integrative cura-tive in treatment of allergic rhinitis can significantly improve clinical symptoms, and no significant adverse reactions, should be popularized and applied.
作者 王海英 慈军
出处 《中国现代医生》 2014年第14期63-65,共3页 China Modern Doctor
基金 浙江省卫生厅课题(2000B003)
关键词 过敏性鼻炎 玉屏风颗粒 地氯雷他定 Allergic rhinitis Yupingfeng particles Loratadine
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