摘要
目的比较糠酸莫米松鼻喷剂和地氯雷他定片剂治疗变应性鼻炎(AR)疗效和安全性。方法入选56例AR患者随机分为两组,每组28例,A组予糠酸莫米松鼻喷剂喷鼻治疗;B组予地氯雷他定片剂口服治疗;疗程均为2周(14d);观察比较其疗效及不良反应。结果每组自身治疗前后相比较均有统计学差异(P<0.05);A、B组间治疗前后相比较,治疗1周差异均无统计学意义(P>0.05);治疗2周均有统计学差异(P<0.05)。A、B组分别发生轻度不良反应1、2例,两组间比较无统计学差异(P>0.05);无严重不良反应发生。结论糠酸莫米松鼻喷剂和地氯雷他定片治疗AR安全、有效。糠酸莫米松鼻喷剂疗效优于地氯雷他定片。
Objective To compare the efficacy and safety between mometasone furoate and descloratadine in treatment of allergic rhinitis (AR) .Methods A total of 56 patients with AR were randomly assigned into two groups.Group A (n=28) took nasal spray of mometasone furoate and Group B (n=28) took oral tablets of descloratadine for 14 days.Results There were statistical differences in the efficacy after treatment compared with baseline before treatment in each group (P0.05) .After one week's treatment,there was no obvious difference between the Group A and B (P0.05) .After two weeks'treatment,there was distinct difference between the two groups (P0.05) .No severe side effects occurred.Slight side effects were found in one case from Group A and in two cases from Group B,between which there existed no obvious difference (P0.05) .Conclusion Mometasone furoate and descloratadine to treat AR is effective and safe.Nasal spray of mometasone furoate's efficacy is better than oral descloratadine tablets'.
出处
《临床军医杂志》
CAS
2010年第4期608-610,共3页
Clinical Journal of Medical Officers
