摘要
目的:研究应用双歧三联活菌片联合蒙脱石散治疗小儿腹泻疗效及安全性,为临床上治疗小儿腹泻提供指导意见。方法:将腹泻患儿120例分成治疗组和对照组各60例,对照组采用常规补液、纠正水电解质紊乱、对症治疗的基础上加用双歧三联活菌片进行治疗,治疗组在对照组的基础上加用蒙脱石散进行治疗,对比两组在治疗前后患儿的体温、大便恢复时间、粪常规、血常规、呕吐、腹痛等临床症状或指标的改善情况以及两组有效率的差异。结果:对治疗组和对照组进行退烧时间、大便恢复正常时间、粪常规回复时间、呕吐缓解时间、腹痛缓解时间、血常规恢复正常时间、脱水纠正时间、总疗程停止时间进行对比差异有统计学意义(P<0.05);治疗组总有效率88.33%明显高于对照组71.67%,差异有统计学意义(P<0.05)。结论:双歧三联活菌片联合蒙脱石散治疗小儿腹泻比单用双歧三联活菌片进行治疗具有更好的临床疗效,各项临床症状或指标恢复正常的时间较单用双歧三联活菌片快。
Objective: To research the curative effect and safety of Bifidobacterium triple viable tablets combined with Montmorillonite powder in treatment of infantile diarrhea,provide guidance for clinical treatment of diarrhea in children. Methods: One hundred and twenty children with diarrhea were divided into treatment group and control group,60 children in each group; the children in control group were treated with conventional fluid infusion,correction of water and electrolyte disorders,symptomatic therapy combined with Bifidobacterium triple viable tablets,while the children in treatment group were added with Montmorillonite powder combined with the therapies used in control group; the improvements of clinical symptoms and parameters( body temperature,bowel movement recovery time,stool routine test,blood routine test,vomiting and abdominal pain) in the two groups were compared; the effective rates in the two groups were also compared.Results: There were statistically significant differences in fever time,bowel movement recovery time,stool routine recovery time,vomiting remission time,abdominal pain remission time,blood routine recovery time,dehydration correcting time and stop time of total course between the two groups( P〈0. 05); the total effective rate in treatment group was 88. 33%,which was statistically significantly higher than that in control group( 71. 67%)( P〈0. 05). Conclusion: The clinical efficacy of Bifidobacterium triple viable tablets combined with Montmorillonite powder in treatment of infantile diarrhea is better than that of simple Bifidobacterium triple viable tablets,and the times for clinical symptoms and parameters return to normal was faster than those of the latter.
出处
《中国妇幼保健》
CAS
北大核心
2014年第16期2618-2620,共3页
Maternal and Child Health Care of China
基金
浙江省台州市卫生局科研项目〔2011AA201B09〕
关键词
双歧三联活菌片
蒙脱石散
小儿腹泻
Bifidobacterium triple viable tablet Montmorillonite powder Infantile diarrhea