摘要
目的：探讨某院假丝酵母菌所致医院感染的危险因素。方法选取该院2011年1月-2013年10月64例假丝酵母菌医院感染患者作为病例组，同期未发生医院感染的64例患者作为对照组，对两组患者的病历资料进行分析。结果医院感染假丝酵母菌以白假丝酵母菌（68．75％）为主，其次为热带假丝酵母菌（15．62％）、光滑假丝酵母菌（9．38％）和克柔假丝酵母菌（6．25％）；感染部位以呼吸道（67．19％）为主，其次为泌尿道（18．75％）、消化道（10．94％）等。单因素分析表明：年龄、住院时间、糖尿病、恶性肿瘤等13个因素是假丝酵母菌医院感染危险因素；多因素logistic回归分析显示，年龄（OR95％ CI：2．57～33．67）、住院时间（OR95％ CI：2．17～25．37）、恶性肿瘤（OR95％ CI：1．04～15．23）、化学治疗（OR95％ CI：1．76～20．63）、使用呼吸机（OR95％ CI：4．67～96．37）是假丝酵母菌医院感染的重要危险因素。结论假丝酵母菌医院感染的危险因素较为复杂，应充分考虑并针对危险因素采取防控措施，降低假丝酵母菌医院感染的发生率。
Objective To explore the risk factors for healthcare-associated infection （HAI）caused by Candidain a hospital.Methods 64 patients with healthcare-associated（HA）Candidainfection in a hospital between January 201 1 and October 2013 were selected as case group,and 64 patients without HACandidainfection during the same period were as control group,clinical data of two groups of patients were analyzed.Results The mainCandidacau-sing HAI were Candidaalbicans（68. 75% ）,followed by Candidatropicalis（15. 62% ）,Candidaglabrata （9.38% ）andCandidakrusei（6.25% ）.The major infection sites were respiratory tract（67.19% ）,urinary tract （18.75% ）and digestive tract（10.94% ）. Univariate analysis showed the risk factors for HA Candidainfection were age,length of hospital stay,diabetes,and malignant tumor and so on;multivariate logistic regression analysis showed that important risk factors for HACandidainfection were age（OR95% CI：2.57-33.67）,length of hospi-tal stay（OR95% CI：2.17-25.37）,malignant tumor（OR95% CI：1.04-15.23）,chemotherapy（OR95% CI：1.76-20.63）,and use of respirator（OR95% CI：4.67-96.37）.Conclusion Risk factors for HACandidainfection are complicated,in order to reduce the incidence of HA Candidainfection,risk factors should be considered,and preventive measures according to risk factors should be made.
出处
《中国感染控制杂志》
CAS
2014年第4期215-217,221,共4页
Chinese Journal of Infection Control
关键词
假丝酵母菌
真菌
医院感染
危险因素
Candida
fungus
healthcare-associated infection
risk factor
