摘要
目的探讨连续性肾脏替代治疗(CRRT)在糖尿病肾病合并急性肾损伤(AKI)中的临床治疗价值。方法选取2009年11月至2012年12月因糖尿病肾病合并AKI就诊于该院的患者157例,根据血液净化的方式分为采用CRRT治疗的观察组(81例)和采用间歇性血液透析(IDH)的对照组(76例),统计两组患者的治疗效果,并对数据进行统计比较。结果两组摆脱替代治疗率及病死率比较,差异无统计学意义(P>0.05)。观察组治疗后急性生理学和慢性健康状况Ⅱ评分为(16.8±4.7)分,摆脱替代治疗所用时间为(12.6±2.8)d,与对照组的(22.6±4.9)分和(16.8±3.4)d比较,差异有统计学意义(P<0.05)。结论 CRRT是糖尿病肾病合并AKI较为安全有效的治疗方法,值得临床推广。
Objective To explore the clinical value of continuous renal replacement therapy （CRRT ）for the treatment of diabetic nephropathy （DN） complicated with acute kidney injury （AKI） .Methods A total of 157 patients with DN complicated with AKI ,treated in this hospital from November 2009 to December 2012 were enrolled and di-vided into CRRT treatment group（n=81） and intermittent hemodialysis（IDH） treatment group（n=76） ,according to blood purification methods .Treatment effect were statistically compared between the two groups .Results There were no significant difference of the rate of getting rid of replacement therapy and mortality between the two groups （P〉0 .05） .After treatment ,the Acute Physiology and Chronic Health Evaluation Ⅱ （APACHE Ⅱ ） score and time needed to get rid of replacement therapy were（16 .8 ± 4 .7） scores and（12 .6 ± 2 .8）d in CRRT treatment group ,which were significantly different with the（22 .6 ± 4 .9） scores and（16 .8 ± 3 .4）d in IDH treatment group（P〈0 .05） .Con-clusion CRRT could be safe and effective for the treatment of DN complicated with AKI ,which might be worth of wildly clinical application .
出处
《检验医学与临床》
CAS
2014年第9期1202-1203,共2页
Laboratory Medicine and Clinic
关键词
糖尿病肾病合并急性肾损伤
连续性肾脏替代治疗
间歇性血液透析
diabetic nephropathy complicated with acute kidney injury
continuous renal replacement thera-py
intermittent hemodialysis
