摘要
血管形成(Neovascularization)是肿瘤生长、浸润和转移的必要条件。影响肿瘤预后的重要因素之一是血管形成,形成的血管可为肿瘤的增长提供营养物质及带走代谢产物。肿瘤分泌的血管内皮生长因子(vascular endothelial growth factors,VEGF)可刺激血管形成,从而间接影响了肿瘤预后。本文针对血管形成与肿瘤预后的研究进展进行综述。
Neovascularization is indisPensable for neoPlasm growth,invasiveness and metastasis. As one significant factor influencing the Prognosis of tumor,neovascularization Plays an imPortant role in Providing nutrient for neoPlasm growth and carrying metabolite away. Vascular endothelial growth factors which secrete by tumors stimulate neoPlasm growth and influence the Prognosis of tumor indirectly as a consequence. We will summarize the research Progress of the relationshiP between neovascularization and the Prognosis of tumor.
出处
《现代肿瘤医学》
CAS
2014年第5期1196-1200,共5页
Journal of Modern Oncology
基金
上海市科学技术委员会科研计划项目课题(编号:11411950602)
关键词
血管形成
血管生成因子
肿瘤预后
neovascularization
angiogenesis factors
Prognosis
