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血清PAB、NT-proBNP、hsCRP对慢性心力衰竭的诊断价值 被引量:3

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摘要 目的探讨血清前白蛋白(PAB)、氨基末端B型利钠肽前体(NT-proBNP)、超敏C反应蛋白(hs-CRP)对慢性心力衰竭(CHF)的诊断价值。方法测定并比较146例CHF组及92例对照组血清PAB、NT-proBNP、hs-CRP水平。结果 CHF组PAB水平明显低于对照组(P<0.05),并随NYHA心功能分级升高而下降。CHF组NT-proBNP、hs-CRP水平则显著高于对照组(均P<0.05),并随NYHA心功能分级升高而上升。PAB与NYHA心功能分级呈负相关(r=-0.502,P<0.05),NT-proBNP、hs-CRP与NYHA心功能分级呈正相关(r=0.430,0.530,P<0.05)。血清PAB与NT-proBNP、hs-CRP分别呈负相关(r=-0.246,-0.256,P<0.05),hs-CRP与NT-proBNP呈正相关(r=0.254,P<0.05)。结论血清PAB、NT-proBNP、hs-CRP在指导CHF的诊断和心功能分级方面有重要价值。
出处 《医药论坛杂志》 2014年第4期72-73,共2页 Journal of Medical Forum
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