摘要
目的探讨心脏磁共振影像钆延迟强化与慢性心力衰竭患者心脏不良事件发生率的相关性。方法根据心脏磁共振影像是否存在钆延迟强化(LGE),将90例慢性心力衰竭患者分为LGE(+)组和LGE(-)组,对其基线资料进行分析,随访2年,记录两组患者心脏不良事件发生情况,以单因素和多因素Cox回归分析心脏不良事件预测因子。结果90例慢性心力衰竭患者,心脏磁共振LGE(+)46例,LGE(-)44例,LGE发生率比较差异无统计学意义(χ^2=1.175,P=0.182)。LGE(+)组氨基末端脑钠肽前体(NT-proBNP)水平明显高于LGE(-)组,差异有统计学意义(t=2.738,P=0.031),其他基线资料比较差异均无统计学意义(P>0.05)。随访结果显示,2年内LGE(+)组心脏不良事件发生率为45.65%,明显高于LGE(-)组的22.73%,差异有统计学意义(χ^2=6.592,P=0.008)。单因素和多因素Cox回归分析显示,钆延迟强化是慢性心力衰竭患者心脏不良事件的独立预测因子(OR=0.638,95%CI:2.013~2.573,P<0.05)。结论慢性心力衰竭患者心脏磁共振影像钆延迟强化强度与心脏不良事件发生率升高相关,可作为预后不良事件的预测因子。
【Objective】To investigate the correlation between late gadolinium enhancement on cardiac magnetic resonance imaging and cardiac adverse events in patients with chronic heart failure.【Methods】According to the presence of late gadolinium enhancement(LGE)in cardiac magnetic resonance imaging,90 patients with chronic heart failure were divided into LGE(+)group and LGE(-)group.Baseline data were analyzed and followed up for 2 years.Cardiac adverse events in the two groups were recorded and assessed by single factor and multivariate Cox regression.【Results】In 90 patients with chronic heart failure,there were 46 cases of cardiac magnetic resonance LGE(+)and 44 cases of LGE(-),the difference in the incidence of LGE was not statistically significant(χ^2=1.175,P=0.182).The level of N-terminal pro-brain natriuretic peptide(NT-proBNP)in LGE(+)group was significantly higher than that in LGE(-)group,and the difference was statistically significant(t=2.738,P=0.031).Other baseline data were compared,and there was no statistical significance(P>0.05).The follow-up results showed that the incidence of adverse cardiac events in the LGE(+)group was 45.65%within two years,which was significantly higher than that in the LGE(-)group(22.73%),and the difference was statistically significant(χ^2=6.592,P=0.008).Univariate and multivariate Cox regression analysis showed that late gadolinium enhancement was an independent predictor of adverse cardiac events in patients with chronic heart failure(OR=0.638,95%CI:2.013 to 2.573,P<0.05).【Conclusion】The intensity of late gadolinium enhancement on cardiac magnetic resonance imaging in patients with chronic heart failure is associated with an increased incidence of adverse cardiac events and can be used as a predictor of adverse prognosis.
作者
王宁博
WANG Ningbo(Nuclear Magnetic Resonance Room,Nanyang Central Hospital,Nanyang,Henan 473000,China)
出处
《中国医学工程》
2019年第8期14-17,共4页
China Medical Engineering
关键词
慢性心力衰竭
心脏磁共振
钆延迟强化
心脏不良事件
chronic heart failure
cardiac magnetic resonance
late gadolinium enhancement
cardiac adverse events
