摘要
目的探讨非那雄胺联合二甲双胍治疗老年良性前列腺增生合并糖尿病的效果。方法75例良性前列腺增生合并糖尿病患者均为2012年4月～2013年9月来我院确诊的病例，采用非那雄胺与二甲双胍联合治疗，比较治疗前后的差异。结果治疗后国际前列腺症状评分、生活质量评分、前列腺体积、前列腺特异性抗原、残余尿量、体质指数及三酰甘油均低于治疗前，最大尿流率高于治疗前，差异有统计学意义（P〈0．05）。结论非那雄胺联合盐酸二甲双胍治疗良性前列腺增生合并糖尿病临床效果较好，两种药物能起到协同作用，可以在临床推广应用。
Objective To investigate the effect of finasteride and combination therapy with metformin in elderly diabetic patients with benign prostatic hyperplasia. Methods Seventy-five cases of benign prostatic hyperplasia patients with diabetes mellitus in this group were selected from April 2012 to September 2013 in our hospital, they used finasteride metformin therapy, the clinical results after and before treatment were compared with statistical methods. Results The international prostate symptom score, quality of life score, prostate volume, prostate-speclfic antigen, residual urine volume, body mass index and triglycerides after treatment were lower than before treatment, the maximum flow rate was higher than before treatment, there were significant difference between after and before treatment （P 〈0.05）. Conclusion Finasteride combined metformin hydrochloride for benign prostatic hyperplasia patients with diabetes have better clinical results, the two drugs with synergistic effect can be used in clinical practice.
出处
《中国现代医生》
2014年第13期62-64,共3页
China Modern Doctor
