摘要
目的:探讨原发性胃淋巴瘤(PGL)的临床特点,以期提高该病的诊治水平。方法:回顾性分析湖北医药学院附属太和医院2003年01月至2013年01月收治的42例原发性胃淋巴瘤患者的临床病理资料。结果:患者多以消化道症状为主要表现,腹痛最常见,占83.3%,其次为恶心、呕吐、黑便和腹部包块。胃镜诊断阳性率为46.1%,高于钡餐及CT,超声胃镜可以协助诊断。DLBCL是其最常见的病理类型。ⅠE期23例、ⅡE期11例、ⅢE期5例、ⅣE期3例。MALToma的预后与DLBCL无显著差异。LDH升高者预后较正常水平者差;ⅠE期、ⅡE期患者预后较ⅢE期、ⅣE期好。结论:PGL临床表现以消化道症状为主,胃镜检查有利于诊断,治疗手段包括手术、化疗及放疗,选用CHOP化疗方案的患者联合美罗华预后较仅行CHOP方案好。
Objective：To investigate the clinical features of primary gastric lymphoma（PGL）. Metbods：A retro- spective analysis of the clinical and pathological datas of 42 cases of primary gastric lymphoma of patients was per- formed. Results：Gastrointestinal symptoms were the mainly performance for most patients. Abdominal pain was most commonly（83.3% ）, followed by nausea, vomiting, melena and abdominal mass. Endoscopy diagnostic positive rate was 46.1% , higher than the barium meal and CT, EUS can help diagnosis. DLBCL was the most common histological type. I E 23 cases, 1I E 11 cases, 11I E 5 cases, 1V E 3 cases. The prognosis of type MALToma has no difference with DL- BCL ones. LDH elevated ones whose prognosis superior than the normal ones. I E, IIE prognosis better than m E, 1VE. Conclusion： Abdominal pain is the most frequent PGL clinical manifestations. Gastroscopycon can help diagno- sis. The treatment methods including surgery, chemotherapy and radiotherapy. CHOP chemotherapy combined ritux- imab had better prognosis than CHOP regimen alone.
出处
《现代肿瘤医学》
CAS
2014年第4期885-888,共4页
Journal of Modern Oncology
关键词
原发性胃淋巴瘤
弥漫性大B细胞淋巴瘤
黏膜相关胃淋巴瘤
美罗华
primary gastric lymphoma
diffuse large B - cell lymphoma
gastric lymphoma of mucosa - associated
rituximab
